A COMBINATION OF A PDE4 INHIBITOR AND A LEUKOTRIENE ANTAGONIST IN THE TREATMENT OF BRONCHIAL AND RESPIRATORY DISORDERS

摘要

Bronchial and respiratory disorders are treated by the separate, sequential,or simultaneous administration of i) an amount of N-(3,5-dichloropyrid-4-yl)-cyclopropylmethoxy-4-difluoromethoxybenzamide, the pyridyl N-oxide thereof, ora pharmaceutically acceptable salt of either compound; and ii) an amount of aleukotriene antagonist, wherein the sum of the first and second amounts is atherapeutically effective amount.