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Evaluation of the Immunologic Impact of RAF Inhibitors to Guide Optimal Combination of RAF Inhibitors and Immunotherapy for the Treatment of Advanced Melanoma.

机译：评估RaF抑制剂对引导RaF抑制剂和免疫疗法治疗晚期黑色素瘤的最佳组合的免疫影响。

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作者
Callahan, M.; Merghoub, T.;
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年度 2016
页码 1-22
总页数 22
原文格式 PDF
正文语种 eng
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Antigens; Tumor cell line; Biological staining and labeling; Culture techniques; Antibodies; Immunotherapy; Cecum; Gene expression; Stimulation (physiology); Melanoma; T cells; Targeted inhibitors;

机译：抗原;肿瘤细胞系;生物染色和标记;培养技术;抗体;免疫疗法;盲肠;基因表达;刺激（生理学）;黑素瘤; T细胞;靶向抑制剂;
入库时间 2022-08-29 10:46:24

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专利

1. Dependence on phosphoinositide 3-kinase and RAS-RAF pathways drive the activity of RAF265, a novel RAF/VEGFR2 inhibitor, and RAD001 (Everolimus) in combination. [J] . Mordant P, Loriot Y, Leteur C, Molecular cancer therapeutics . 2010,第2期

机译：对磷酸肌醇3-激酶和RAS-RAF途径的依赖共同驱动RAF265（一种新型RAF / VEGFR2抑制剂）和RAD001（依维莫司）的活性。
2. Phase Ib Study of Combination Therapy with MEK Inhibitor Binimetinib and Phosphatidylinositol 3-Kinase Inhibitor Buparlisib in Patients with Advanced Solid Tumors with RAS/RAF Alterations [J] . Zeitschrift fur Arznei- und Gewurzpflanzen . 2020,第1期

机译：用RA / RAF改变的晚期实体肿瘤患者与MEK抑制剂Binimetinib和磷脂酰肌醇3-激酶抑制剂Buparlisib的相位IB研究
3. Phase Ib Study of Combination Therapy with MEK Inhibitor Binimetinib and Phosphatidylinositol 3-Kinase Inhibitor Buparlisib in Patients with Advanced Solid Tumors with RAS/RAF Alterations [J] . Bardia Aditya, Gounder Mrinal, Rodon Jordi, The oncologist . 2020,第1期

机译：用RA / RAF改变的晚期实体肿瘤患者与MEK抑制剂Binimetinib和磷脂酰肌醇3-激酶抑制剂Buparlisib的相位IB研究
4. Development of Combined PK/PD Studies of RAF/MEK/mTOR Inhibitors for the Treatment of Pediatric Low-Grade Astrocytomas by MALDI Mass Spectrometry Imaging [C] . David Calligaris, Xiaohui Liu, Daniel Feldman, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：RAF / MEK / MTOR抑制剂组合PK / PD研究的研制治疗MALDI质谱成像治疗儿科低级星形细胞瘤
5. Small Molecule Inhibitors of Cell Migration and The Subcellular Localization of Raf Kinase Inhibitor Protein [D] . Argueta, Christian 2012

机译：细胞迁移的小分子抑制剂和Raf激酶抑制剂蛋白的亚细胞定位
6. Phase Ib Study of Combination Therapy with MEK Inhibitor Binimetinib and Phosphatidylinositol 3‐Kinase Inhibitor Buparlisib in Patients with Advanced Solid Tumors with RAS/RAF Alterations [O] . Aditya Bardia, Mrinal Gounder, Jordi Rodon, 2020

机译：MEK抑制剂Binimetinib和磷脂酰肌醇3-激酶抑制剂Buparlisib联合治疗晚期实体瘤伴RAS / RAF改变的Ib期研究
7. Evaluation of the Immunologic Impact of RAF Inhibitors to Guide Optimal Combination of RAF Inhibitors and Immunotherapy for the Treatment of Advanced Melanoma [O] . Margaret Callahan, Taha Merghoub 2014

机译：评价RAF抑制剂免疫影响，以指导RAF抑制剂和免疫疗法的最佳组合治疗晚期黑色素瘤
8. Evaluation of the Immunologic Impact of RAF Inhibitors to Guide Optimal Combination of RAF Inhibitors and Immunotherapy for the Treatment of Advanced Melanoma. [R] . Callahan, M., Merghoub, T. 2014

机译：评估RaF抑制剂对引导RaF抑制剂和免疫疗法治疗晚期黑色素瘤的最佳组合的免疫影响。

Evaluation of the Immunologic Impact of RAF Inhibitors to Guide Optimal Combination of RAF Inhibitors and Immunotherapy for the Treatment of Advanced Melanoma.

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