Disclosed is a peptide useful for a specific immunotherapy, particularly a cancer peptide vaccine therapy, for an HLA-A24- or HLA-A2-positive malignant tumor patient. Specifically disclosed is a peptide which is an EphB6v-peptide-derived peptide fragment having the amino acid sequence depicted in SEQ ID NO:3, which can bind to an HLA-A24 or HLA-A2 molecule, and which has a peptide-specific CTL-inducing ability. More specifically disclosed are peptides depicted in SEQ ID NOs: 4 to 7.
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机译:公开了对于HLA-A24-或HLA-A2阳性的恶性肿瘤患者可用于特异性免疫疗法,特别是癌肽疫苗疗法的肽。具体公开了一种肽,其是具有SEQ ID NO:3所示氨基酸序列的EphB6v-肽衍生的肽片段,其可以结合HLA-A24或HLA-A2分子,并且具有肽特异性CTL -诱导能力。更具体地公开了SEQ ID NO:4至7所示的肽。
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