首页> 外国专利> MEDICINAL AGENT FOR PREVENTING PROGRESSION OF APOPTOTIC AND JUGULATING NECROTIC CHANGES IN THE ORGANISM TISSUES

MEDICINAL AGENT FOR PREVENTING PROGRESSION OF APOPTOTIC AND JUGULATING NECROTIC CHANGES IN THE ORGANISM TISSUES

机译:防止有机体中凋亡和破坏性神经变化的药物

摘要

The invention relates to medicine, in particular, to a medicinal agent for preventing (decelerating) the progression of the apoptotic changes in the cells of various organs and the transformation thereof into necrotic tissue damage. The inventive agent comprises at least one type of 3-oxypyridine or the derivative of 3-oxypyridine, at least one type of purine or the derivative of purine or a nicotine-amide-adenine-dinucleotide. The preferred 3-oxypyridin derivative is embodied in the form of 3-oxy-6-methyl-2-ethyl pyridine succinate. The preferred purine derivative is embodied in the form of inosine. The said medicinal agent can also contain an L-carnitine, alphoscerate choline, and be administered in the form of an injection, a pill, capsule, or suppository. The inventive medicinal agent exhibits a wide therapeutic range and low toxicity, which makes it possible to remove or minimize the causes of apoptotic change activation, to reduce the degree of necrotic tissue damage generated by the pathological process of different etiologies and to decelerate the organism aging process.
机译:本发明涉及药物,特别是涉及一种用于预防(减速)各种器官细胞的凋亡变化的进程以及将其转化为坏死组织损伤的药物。本发明的试剂包括至少一种类型的3-氧吡啶或3-氧吡啶的衍生物,至少一种嘌呤或嘌呤或烟碱-酰胺-腺嘌呤-二核苷酸的衍生物。优选的3-氧吡啶衍生物以3-氧-6-甲基-2-乙基吡啶琥珀酸酯的形式体现。优选的嘌呤衍生物以肌苷的形式体现。所述药物还可以包含左旋肉碱,阿魏酸胆碱,并且可以以注射剂,丸剂,胶囊剂或栓剂的形式给药。本发明的药物表现出宽广的治疗范围和低毒性,这使得可以消除或最小化凋亡变化激活的原因,减少由不同病因的病理过程产生的坏死组织损害的程度,并减缓生物衰老。处理。

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