Genetic variation on CHR5p12 and 10q26 as markers for use in breast cancer risk assessment, diagnosis, prognosis and treatment

摘要

The invention pertains to certain genetic variants on Chr10q26 as susceptibility variants of breast cancer. Methods of disease management, including diagnosing increased and/or decreased susceptibility to breast cancer, methods of predicting response to therapy and methods of predicting prognosis using such variants are described. The invention further relates to kits useful in the methods of the invention.