The present invention, real time monitoring of nucleic acid amplification reaction products for while performing nucleic acid amplification reactions such as polymerase chain reaction, a large number of samples in small amounts, can be monitored in real time generation of reaction products generated during the reaction relates to a device. Specifically, in order to efficiently separate the interference of excitation light and fluorescence, the invention includes a polarizer (Polarizer), polarizing beam splitter (Polarizing Beam Splitter), the polarization converter and (Polarization Converting System) on real-time monitoring device of biochemical reactions. [Selection Figure Figure 2
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