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Nucleic Acid molecules and Collections Thereof, Their Application and Modification

机译:核酸分子及其集合,应用和修饰

摘要

The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof.
机译:本发明提供了表征包含源自细胞的核酸的样品的方法。该方法包括确定样品是否包含至少一种至少一种根据本发明的新的微小RNA(miRNA)或其哺乳动物直系同源物的最小序列,并且基于存在或不存在miRNA来表征样品。本发明进一步提供了核酸分子及其集合及其在治疗和诊断应用中的用途。本发明还提供了鉴定miRNA分子或其前体分子的方法。

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