An implantable medical device having a lead retention assembly is disclosed herein. In one embodiment, the lead retention assembly comprises at least two receptacles configured to receive a connective end of a respective electrical lead, a support member, a first side clamp configured to define a first port in conjunction with the support member, a second side clamp configured to define a second port in conjunction with the support member, and a fastener configured to urge both the first and second side clamps toward the support member upon actuation of the fastener.
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