Methanesulfonate acid ethyl ester (3 - (2 - ((4 - (Hexyloxy - carbonylamino imino methyl) - phenylamino) - methyl - 1 - methyl) - 1H benzimidazole carbonyl - 5 - (pyridin-2-yl) - amino) - propionic acid and its use as medicine

摘要

Compound acid ethyl ester methanesulfonate [3 - (2 - ((4 - (Hexyloxy - carbonylamino imino methyl) phenylamino] methyl} - 1 - methyl - 5 - 1H benzimidazole carbonyl) - (pyridin-2-yl) - amino] - propionic acid in Crystalline modifications I and II as hemihydrate, and its use as medicine for tra Treatment of diseases mediated by the inhibition of thrombin.Claim 1: The acid ethyl ester methanesulfonate [3 - (2 - ((4 - (hexiloxicarbonilamino imino methyl) - phenylamino] methyl} - 1 - methyl - 5 - 1H benzimidazole carbonyl) - (pyridin-2-yl) - amino] - propionic acid in Crystalline form, characterized by a Point fusion tp.f. = 120 + - 5sc (hemihydrate (Determination) Inated by DSC Peak; Evaluation; heating rate: The C / min).