Crystal structure and metabolic activity of 4-(thien-2-yl)-2-methyl-5-oxo-145678-hexa­hydro­quinoline-3-carb­oxy­lic acid eth­oxy­carbonyl­phenyl­methyl­ester

摘要

In the title compound, C25H25NO5S, which exhibits metabolism-regulating activity, the 1,4-di­hydro­pyridine ring adopts a flattened boat conformation while the cyclo­hexenone ring is in an envelope conformation. Mol­ecules in the crystal are assembled into C(6) chains along the a-axis direction via N—H⋯O hydrogen bonds. The thienyl fragment is disordered over two sets of sites in a 0.7220 (19):0.2780 (19) ratio.