N-(2-Aminophenyl) -4-(Piperidin-4-yl)Benzamide Derivatives Useful as Inhibitors of Histone Deacetylase (HDAC)

摘要

Derivatives of N - (2 - amino phenyl) - 4 - (4 - Bbrydyn IL) benzamide as useful studies of histone Dey Asytylaz (HDAC N. (2-Aminophenyl) - 4 - (Piperidin-4-yl) Benzamide Derivatives Useful as Inhibitors of Histone Deacetylase (HDAC) Almlkhs The invention relates to benzamide compounds as I: compound of formula (I): (1) where it R1 be pyrazole ring associated with the C which is to be replaced with one or more groups al Mukhtar Mimi smallC1-4 alkyl, cyclo alkyl, and C3-4 and C1-4 Alkwksy, C3-4 cyclo Alkwksy; or acceptable salt or a Sydlanyaan initial drug. The invention also relates to processes for preparing such compounds, pharmaceutical Wbtrkybat containing them and their use in the manufacture of medicament for use as a countermeasure to prevent and cure. Tumors or other reproductive cases, which are sensitive to inhibit the enzyme histone de Asytylaz (HDAC).