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SPHENISCINES AND PEPTIDES ANTIMICROBIAL ANALOGS FOR FOOD PRESERVATION.

机译:用于食品保鲜的片状和肽类抗菌物类似物。

摘要

Peptide or an analogue of spheniscin that has an antimicrobial activity and that comprises three intramolecular bonds, and that responds to the following formula (II): ** (See formula) ** In which: - Xaa responds to the following formula: - Xaa1-Xaa2- (SEQ ID NO.2), in which Xaa1 represents a -NH2 group or a peptide moiety of 1 to 13 amino acids, and Xaa2 is Ser-Phe-Gly-Leu; - Xab responds to the following formula: -Xab1-Xab2-Xab3-Xab4-Xab5- (SEQ ID NO.3), and Xab3 represents a peptide moiety that responds to the following formula: -Xab3.1-Xab3.2- ( SEQ ID NO.4), - Xac responds to the following formula: -Xac1-Xac2-Xac3-Xac4- (SEQ ID NO.5), in which Xac2 is His or Arg - Xad with the following sequence: -Xad1- Xad2-Xad3-xad4-xad5-xad6-Xad7-Xad8-Xad9- (SEQ ID NO.6), in which Xad2 is Pro or Phe and Xad3 is Pro - Xae responds to the following sequence: -Xae1-Xae2-Xae3 -Xae4-Xae5- (SEQ ID NO.7), in which Xae2 is Gln or Arg and Xae5 is Gln; - Xaf responds to the following sequence: -Xaf1-Xaf2-Xaf3-Xaf4- (SEQ ID NO.8) and Xaf2 and / or Xaf3 is Val; and - Ca1, Ca2, Ca3, Ca4, Ca5 and Ca6, are sulfur amino acids.
机译:具有抗菌活性并包含三个分子内键并响应以下式(II)的肽或蝶霉素类似物:**(请参见公式)**其中:-Xaa响应以下式:-Xaa1 -Xaa2-(SEQ ID NO.2),其中Xaa1代表-NH2基团或1至13个氨基酸的肽部分,并且Xaa2是Ser-Phe-Gly-Leu; -Xab响应以下分子式:-Xab1-Xab2-Xab3-Xab4-Xab5-(SEQ ID NO.3),并且Xab3代表响应以下分子式的肽部分:-Xab3.1-Xab3.2-( SEQ ID NO.4),-Xac响应以下公式:-Xac1-Xac2-Xac3-Xac4-(SEQ ID NO.5),其中Xac2是His或Arg-Xad,具有以下序列:-Xad1- Xad2 -Xad3-xad4-xad5-xad6-Xad7-Xad8-Xad9-(SEQ ID NO.6),其中Xad2为Pro或Phe,Xad3为Pro-Xae响应以下序列:-Xae1-Xae2-Xae3 -Xae4 -Xae5-(SEQ ID NO.7),其中Xae2是Gln或Arg,而Xae5是Gln; -Xaf响应以下序列:-Xaf1-Xaf2-Xaf3-Xaf4-(SEQ ID NO.8)和Xaf2和/或Xaf3为Val; -Ca1,Ca2,Ca3,Ca4,Ca5和Ca6是硫氨基酸。

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