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KETOCONAZOLE-DERIVATIVE ANTAGONISTS OF HUMAN PREGNANE X RECEPTOR AND USES THEREOF
KETOCONAZOLE-DERIVATIVE ANTAGONISTS OF HUMAN PREGNANE X RECEPTOR AND USES THEREOF
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机译:人孕烷X受体酮康唑衍生物的拮抗剂及其用途
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摘要
The application discloses ketoconazole derivatives that are antagonists of the human pregnane X receptor (PXR), methods of preparing the derivatives, uses of the derivatives with drug therapy, and methods of inhibiting tumor cell proliferation and multidrug resistance using inhibitors of PXR.
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