REGRESSION OF ESTABLISHED ATHEROSCLEROTIC PLAQUES, AND TREATING SUDDEN-ONSET ASTHMA ATTACKS, USING PARP INHIBITORS

摘要

A method is disclosed for treating and inducing the regression of established atherosclerotic plaques. A method is disclosed fortreating asthma, including treatment of an ongoing asthma attack. In both cases, treatment with PARP inhibitors, such as the PARP inhibitor TIQ-A (Thieno[2,3-c]isoquinolin-5-one), can lead to regression of existing disease and symptoms.