首页> 外国专利> use of low density oxidized lipoprotein immunotherapy, method for inducing regression of atherosclerotic plaques in an individual, use of at least one ldl antibody or at least one oxidized epitope of ldl, method for combating cardiovascular disease associated with atherosclerosis, use of at least an antibody molecule or at least one oxidized epitope of ldl and a statin, pharmaceutical formulation, part kit, methods for identifying an antibody that induces regression of atherosclerotic plaques in an individual and for identifying an agent that induces regression of atherosclerotic plaques in an individual, antibody, pharmaceutical composition, and antibody use

use of low density oxidized lipoprotein immunotherapy, method for inducing regression of atherosclerotic plaques in an individual, use of at least one ldl antibody or at least one oxidized epitope of ldl, method for combating cardiovascular disease associated with atherosclerosis, use of at least an antibody molecule or at least one oxidized epitope of ldl and a statin, pharmaceutical formulation, part kit, methods for identifying an antibody that induces regression of atherosclerotic plaques in an individual and for identifying an agent that induces regression of atherosclerotic plaques in an individual, antibody, pharmaceutical composition, and antibody use

机译:低密度氧化脂蛋白免疫疗法的应用,在个体中诱导动脉粥样硬化斑块消退的方法,至少一种ldl抗体或ldl的至少一种氧化表位的使用,与动脉粥样硬化相关的心血管疾病的防治方法,至少一种抗体的使用分子和至少一种Idl的氧化表位和他汀类药物,药物制剂,部分试剂盒,鉴定在个体中诱导动脉粥样硬化斑块消退的抗体和鉴定在个体中诱导动脉粥样硬化斑块消退的药剂的方法,抗体,药物组合物和抗体用途

摘要

USE OF IMMUNOTHERAPY AGAINST LOW OXIDED DENSITY LIPOPROTEIN, METHOD FOR INDUCING REGULATION OF AEROSCLEROTIC PLATES IN AN INDIVIDUAL, USE OF AT LEAST ONE ANTIBODY OR AT LEAST ONE OXIDIZED EPOSTATE OF COMBINED COMBINATION, AN ANTIBODY MOLECULE OR AT LEAST AN OXIDIZED EPYPE OF LDL AND A STATINE, PHARMACEUTICAL FORMULATION, PARTS KIT, METHODS FOR IDENTIFYING AN ANTIBODY THAT INDUCES REGULATION OF ATEROSCLEROTIC PLATES IN AN INDIVIDUAL AND AGRICULTURAL PLATES AN INDIVIDUAL, ANTIBODY, PHARMACEUTICAL COMPOSITION, AND USE OF ANTIBODY. The use of immunotherapy against oxidized LDL to induce regression of pre-existing atherosclerotic lesions in an individual. Immunotherapy can be passive immunotherapy using antibodies that bind to epitopes present in oxidized LDL, or active immunotherapy using a vaccine composition to induce an immune response against epitopes present in oxidized LDL.
机译:使用针对低氧化密度脂蛋白的免疫疗法,在个体中诱导调节气脂板的方法,至少使用一种抗体,或者使用至少一种氧化联苯胺联合酶的混合形式,一种抗体或一种胶状多态抗体,药物配方,零件套件,识别可调控个体和农用平台中厌氧菌板调控的抗体的方法,个体,抗体,药物成分以及抗体的使用。使用抗氧化LDL的免疫疗法诱导个体中已存在的动脉粥样硬化病变消退。免疫疗法可以是使用与氧化的LDL中存在的表位结合的抗体的被动免疫疗法,或者是使用疫苗组合物诱导针对氧化的LDL中存在的表位的免疫应答的主动免疫疗法。

著录项

  • 公开/公告号BRPI0615313A2

    专利类型

  • 公开/公告日2012-12-04

    原文格式PDF

  • 申请/专利权人 BIOINVENT INTERNATIONAL AB;

    申请/专利号BR2006PI15313

  • 发明设计人 ROLAND CARLSSON;JAN NILSSON;

    申请日2006-09-04

  • 分类号C07K16/18;A61K31/33;A61K39;A61K39/395;A61P9/10;G01N33/53;G01N33/68;

  • 国家 BR

  • 入库时间 2022-08-21 16:42:21

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