METHOD FOR SCREENING A METASTASIS INHIBITOR THROUGH MEASURING METHYLATION OF E-CADHERIN PROMOTER SITE

摘要

PURPOSE: A method for screening a metastasis inhibitor is provided to massively and rapidly select the inhibitor and to develop anticancer drug.;CONSTITUTION: A method for screening a metastasis inhibitor comprises: a step of culturing cancer cells; a step of treating candidate materials to the cancer cells; a step of treating ROS(reactive oxygen species) to the cancer cells; a step of measuring methylation of CpG island of E-cadherin gene promoter in the cancer cells; and a step of selecting candidate material of which methylation is reduced.;COPYRIGHT KIPO 2010