The invention relates to a method for operating an industrial scale installation, especially a power plant installation, according to which a number of installation operating parameters characterising the operating state of the technical installation, and a number of component operating parameters respectively relevant to a number of selected components of the technical installation, are monitored and stored in a memory device (2). A fatigue characteristic value characterising the current fatigue state of each component is determined for the or each selected component as required, on the basis of the stored installation operating parameters and/or the stored associated component operating parameters. The aim of the invention is to especially develop an operation of the installation which especially protects resources. To this end, an associated fatigue prognosis value is determined from the fatigue characteristic value characterising the current fatigue state for the or each selected component, on the basis of guiding parameters characterising a planned change of state.
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