The high throughput screening of the metabolism obstacle which uses the laser desorption ion source which is connected to the mass analyzer

摘要

The high throughput screening of the metabolism obstacle which uses the laser desorption ion source (for example, MALDI) which is connected to the mass analyzer and method and the kit for analyzing are offered. Metabolism obstacle, amino acid, can be organic acid or obstacle of fatty acid oxidation. It can analyze the obstacle of one group at high velocity. Method and the kit of this invention especially are useful because of the newborn baby screening (NBS) of metabolism obstacle. Method of this invention furthermore the ion which it occurs with ion source collision damping/can include the fact that it cools with the damping gas.