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GENOMIC EDITING OF GENES INVOLVED IN AUTISM SPECTRUM DISORDERS
GENOMIC EDITING OF GENES INVOLVED IN AUTISM SPECTRUM DISORDERS
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机译:自闭症谱系障碍基因的基因编辑
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摘要
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with ASD. In particular, the animals or cells are generated using a zinc finger nuclease-mediated editing process. Also provided are methods of using the genetically modified animals or cells disclosed herein to study ASD development and screen agents for assessing their effect on progression or symptoms of an ASD.
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