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Substance having antioxidant, geroprotective and anti-ischemic activity and method for the preparation thereof

机译:具有抗氧化,抗保护和抗缺血活性的物质及其制备方法

摘要

The invention relates to the field of medicine, namely to new biologically active compounds, particularly to 2,4,6-trimethyl-3-hydroxypyridine derivatives and salts thereof (compound 1) having antioxidant, geroprotective and anti-ischemic action. The salts of compound (1) are prepared by reacting equimolecular quantities of 2,4,6-trimethyl-3-hydroxypyridine and dicarboxylic in solution of a lower alcohol at a temperature of 60-100° C. with following treatment of the reaction mass with an organic solvent and maintaining for 2-5 h at 10-15 ° C.
机译:本发明涉及医学领域,即涉及新的生物活性化合物,尤其涉及具有抗氧化,抗保护和抗缺血作用的2,4,6-三甲基-3-羟基吡啶衍生物及其盐(化合物1)。通过使等摩尔量的2,4,6-三甲基-3-羟基吡啶和二羧酸在低级醇的溶液中在60-100℃的温度下反应,然后对反应物质进行处理,来制备化合物(1)的盐。用有机溶剂并在10-15°C下保持2-5 h。

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