首页> 外国专利> Method of forming bioabsorbable drug delivery devices

Method of forming bioabsorbable drug delivery devices

机译:形成生物可吸收药物输送装置的方法

摘要

A bioabsorbable drug delivery device and various methods of making the same. The devices are preferably formed from bioabsorbable materials using low temperature fabrication processes, hereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. Radiopaque markers may also be incorporated into, or onto, the devices. The devices may be generally tubular helical stents comprised of a solid ladder or an open lattice configuration, or a hybrid combination thereof. The tubular helical stents are generally formed from precursor fibers, films or tubes. The solid ladder configuration provides increased radiopacity and increased radial strength, whereas the open lattice configuration provides better endothelialization and fluid flow through the stent. The drug or other agent delivery capacity of the devices may provide local or regionalized drug or other agent delivery, or a combination thereof, with more consistent concentrations of drugs or other agents delivered from the device to the treatment site along the entire length of the device.
机译:可生物吸收的药物输送装置及其各种制造方法。所述装置优选地使用低温制造工艺由可生物吸收的材料形成,由此将药物或其他生物活性剂掺入到装置内或装置上,并且在加工过程中药物或其他剂的降解最小化。不透射线的标记物也可以结合到装置中或装置上。装置通常可以是由实心梯子或开放格子构型或其混合组合组成的管状螺旋支架。管状螺旋支架通常由前体纤维,膜或管形成。实心梯形结构提供了更高的射线不透性和径向强度,而开放式格子结构提供了更好的内皮化和通过支架的流体流动。装置的药物或其他药剂递送能力可提供局部或区域性药物或其他药剂递送,或其组合,并且沿着装置的整个长度从装置递送到治疗部位的药物或其他药剂的浓度更加一致。 。

著录项

  • 公开/公告号US7927529B2

    专利类型

  • 公开/公告日2011-04-19

    原文格式PDF

  • 申请/专利权人 VIPUL BHUPENDRA DAVE;

    申请/专利号US20080244622

  • 发明设计人 VIPUL BHUPENDRA DAVE;

    申请日2008-10-02

  • 分类号B29C47/04;

  • 国家 US

  • 入库时间 2022-08-21 18:10:12

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号