Multiparticulate controlled release selective serotonin reuptake inhibitor formulation and the use thereof

摘要

In the present invention, there is disclosed a multiparticulate controlled release selective serotonin reuptake inhibitor (SSRI) formulation for oral administration comprising particles of fluvoxamine or a pharmaceutically acceptable salt thereof coated with rate-controlling polymer, which allows controlled release of said SSRI, over a period of not less than about 12 hours following oral administration. There is also disclosed the use of the above-indicated formulation in the treatment of depression or obsessive-compulsive disorder.