gene construct comprising the gene encoding the protein Kapy genetically modified with the same non-human animal.

摘要

gene construct comprising the gene encoding the protein KAP and genetically modified non-human animal with the same.; The present invention relates to a gene construct comprising the gene of kidney androgen-regulated protein (KAP) mouse under the control of a promoter specific expression in kidney tissue. cellular systems genetically modified non-human animals comprising such a construction and are useful for the evaluation of the mechanisms involved in arterial hypertension and various kinds of damage described nephrology.