The present invention relates to a device for use in delivering a biologically active agent, in particular a therapeutic or prophylactic nucleic acid, to the ocular sphere of a subject. The device of the invention is designed for the administration of the active agent to the ciliary body tissue(s) or cells and/or to the extra-ocular muscle tissue or cells of the subject, and comprises: (i) at least one means for injecting the composition into said tissue(s) or cells, wherein said injection means is an injection needle electrode, or a microneedle array comprising at least one injection needle electrode, (ii) a means for sensing when the needle has been inserted to a sufficient depth for injection of the composition to commence, said depth being comprised between 0.1 and 10 mm, (iii) a means to position said injection means, said positioning means being adapted to be reversibly applied on the surface of the sclera or eye conjuctiva.
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