PYRIMIDINE DERIVATIVES AND THEIR APPLICATION AS RECEPTOR P2Y12 ANTAGONISTS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention relates to derivatives of 4-aminocarbonylpyrimidine of formula (I).;EFFECT: invention is applicable as P2Y₁₂ receptor antagonists for treatment and/or prevention of diseases or disease states of peripheral vessels, as well as vessels, supplying internal organs, vessels of liver and kidneys, in treatment and/or prevention of cardiovascular and cerebrovascular diseases and states, associated with aggregation of platelets, including thrombosis in humans and mammals.;26 cl, 500 ex