METHOD FOR MAKING SERUM FOR DIAGNOSING BOVINE Q FEVER IN INDIRECT IMMUNOFLUORESCENCE TEST

摘要

FIELD: medicine, veterinary science.;SUBSTANCE: invention refers to veterinary science. A method involves hyperimmunisation of rabbits with an antigen with scheduled introduction of the immune-stimulating agent levamizole in the first and fourth day of hyperimmunisation, dynamic studying of antibody synthesis on the 7th, 14th, 21st and 30th days, exsanguination of the rabbits and production of serum. Antigen is vaccine strain C.burnetii M-44 inactivated by heating +70° for 30 minutes.;EFFECT: method allows producing Q fever serum with a high diagnostic antibody titres, as well as increasing diagnostic accuracy in bovine Q fever.;5 tbl