Protein fragmentary complementary analysis in order to detect the interaction of the protein and the protein, the protein and the low-molecular and the protein nuclear acid which are based on the colon bacillus TEM1 lactamase (PCA)

摘要

This invention (A) (1) first fragment of the reporter molecule which at least is connected to first interaction domain and, produces the second fragment of the reporter molecule which at least is connected to second interaction domain, or (2) produces the nuclear acid which the aforementioned first fragment and second fragment the cord/code is done, that backward description nuclear acid molecule the step which produces the product which the cord/code has been done and, next, (B) step and (C) it operates the domain of the aforementioned two mutually can react with the substrate of penicillin class or the substrate of cephalosporin class, detecting the reporter molecular activity which was re-constructedThe analysis method of including with the step which it does has been explained.