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INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17-ALPHA-ACETOXY-11 BETA- -4-(N,N-DIMETHYLAMINO)-PHENYL-19NORPREGNA-4,9-DIENE-3,20-DIONE AND INTERMEDIATES O THE PROCESS
INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17-ALPHA-ACETOXY-11 BETA- -4-(N,N-DIMETHYLAMINO)-PHENYL-19NORPREGNA-4,9-DIENE-3,20-DIONE AND INTERMEDIATES O THE PROCESS
A new industrial process for the synthesis of solvate-free 17-acetoxy-11-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione [CDB-2914] of formula (I) which is a strong antiprogestogene and antiglucocorticoid agent. The invention also relates to compounds of formula (VII) and (VIII) used as intermediates in the process.
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