Method for identifying or evaluating compounds useful in the field of fragrances and flavors.

摘要

Method of identifying or evaluating test compounds, wherein the compound or at least one of its metabolites, is an odorant, or a precursor of an odorant or a modulator of the perception of an odorant comprising a) providing a space for the head of a test compound, saturated, optionally diluted, b) Inhalation of said headroom by a human testee c) emission of breath exhaled by the human testee d) Analysis of exhaled breath by a detection method selected from a method of trapped volatiles exhaled in a resin, desorption of the bound material from the resin and material analysis desorbed by gas chromatography coupled with mass spectrometry (Metabo-GM), a method the exhaled volatile metabolites generated in vivo are exhaled an interface to an analysis device which records the mass spectra using a spectrometer d and mass quadrupole equipped with an ion source for chemical ionization at atmospheric pressure able to measure the dynamic ranges of the volatiles (Metabospace) and Mass Spectrometry Reaction Proton Transfer (PTR-MS), or a combination thereof.