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AMINOSTEROID COMPOUNDS FOR TOPIC LOCAL APPLICATION FOR SKIN-MUCOSA DECOLONISATION OF STAPHYLOCOCCUS AUREUS

机译:局部应用金黄色葡萄球菌皮肤粘膜去殖民化用氨脂类化合物

摘要

The present invention relates to the use of a compound selected from among squalamine, or an aminosteroid compound analogous to squalamine, for local topical application for mucous/cutaneous decolonization of Staphylococcus aureus, said squalamine-analogous aminosteroid compound having a general formula that includes a skeleton of Formula (I) below, onto which at least one -NHR polyamine chain is grafted, R being an optionally substituted hydrocarbon chain comprising at least one - NH2 group.
机译:本发明涉及选自角鲨胺或类似于角鲨胺的氨基类固醇化合物的化合物在局部局部应用金黄色葡萄球菌的粘液/皮肤非殖民化中的用途,所述角鲨胺类似物的具有类固醇骨架的通式的氨基甾类化合物式(I)的式(I)中,至少一个-NHR多胺链被接枝在其上,R为包含至少一个-NH 2基团的任选取代的烃链。

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