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LOCAL TOPICAL APPLICATION AMINOSTEROID COMPOUNDS FOR MUCOUS/CUTANEOUS DECOLONIZATION OF STAPHYLOCOCCUS AUREUS

机译:金黄色葡萄球菌的粘液/瞬时非殖民化局部应用类氨基化合物

摘要

The present invention relates to the use of a compound selected from among squalamine, or an aminosteroid compound analogous to squalamine, for local topical application for mucous/cutaneous decolonization of Staphylococcus aureus, said squalamine-analogous aminosteroid compound having a general formula that includes a skeleton of Formula (I) below, onto which at least one -NHR polyamine chain is grafted, R being an optionally substituted hydrocarbon chain comprising at least one - NH2 group.
机译:本发明涉及选自角鲨胺或类似角鲨胺的氨基类固醇化合物的化合物在局部局部施用金黄色葡萄球菌的粘液/皮肤非定殖中的用途,所述角鲨胺类似的氨基甾体化合物具有通式,包括以下式(I)的骨架,在其上接枝有至少一个-NHR多胺链,R为包含至少一个-NH 2基团的任选取代的烃链。

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