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A colorectal cancer marker genes?proteins translated from the genes and a diagnostic kit using the same

机译:大肠癌标志物基因?从这些基因翻译的蛋白质和使用该蛋白质的诊断试剂盒

摘要

PURPOSE: A marker for diagnosing colon cancer and a kit for diagnosing colon cancer using the same are provided to specifically enhance expression in colon cancer cells. CONSTITUTION: A marker for diagnosing colon cancer contains overexpressing genes. A microarray for diagnosing colon cancer contains an oligonucleotide having an entire or partial FLJ14346, CDK4, CASP2, FKBP4, TBL3, GTF3C2, NOL5A, COCH, C1orf43, or PTDSS1 gene or complementary oligonucleotide thereof. A method for detecting the marker gene for diagnosing colon cancer comprises: a step of detecting the expression level of FLJ14346, CDK4, CASP2, FKBP4, TBL3, GTF3C2, NOL5A, COCH, C1orf43 or PTDSS1; and a step of selecting an individual of which an expression level is higher than the expression level of a healthly person. A kit for diagnosing colon cancer comprises a sensor for amplifying FLJ14346, CDK4, and CASP2.
机译:目的:提供用于诊断结肠癌的标志物和使用该标志物的用于诊断结肠癌的试剂盒,以特异性增强结肠癌细胞中的表达。构成:诊断结肠癌的标志物包含过度表达的基因。用于诊断结肠癌的微阵列包含具有完整或部分FLJ14346,CDK4,CASP2,FKBP4,TBL3,GTF3C2,NOL5A,COCH,C1orf43或PTDSS1基因的寡核苷酸或其互补寡核苷酸。一种用于检测结肠癌的标志基因的方法,包括:检测FLJ14346,CDK4,CASP2,FKBP4,TBL3,GTF3C2,NOL5A,COCH,C1orf43或PTDSS1的表达水平的步骤;以及选择表达水平高于健康人表达水平的个体的步骤。诊断结肠癌的试剂盒包括用于扩增FLJ14346,CDK4和CASP2的传感器。

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