DETECTION OF MYELODYSPLASTIC SYNDROME (MDS) USING SOMATIC MUTATION

摘要

PROBLEM TO BE SOLVED: To provide an inspection method for detecting myelodysplastic syndrome (MDS) with genetic polymorphism, and to provide a nucleotide used for detection.;SOLUTION: There are provided 20 kinds of the following mutant nucleic acids and a method for detecting them: (1)SF3B1_E622D, (2)SF3B1_E622D, (3)SF3B1_H662D, (4)SF3B1_H662Q, (5)SF3B1_H662Q, (6)SF3B1_K666E, (7)SF3B1_K666N, (8)SF3B1_K666N, (9)SF3B1_K666T, (10)SF3B1_K666R, (11)SF3B1_K700E, (12)SF3B1_R625C, (13)SF3B1_R625L, (14)SRSF2_P95H, (15)SRSF2_P95L, (16)SRSF2_P95R, (17)U2AF35_Q157R, (18)U2AF35_Q157P, (19)U2AF35_S34F, (20)U2AF35_S34Y.;COPYRIGHT: (C)2013,JPO&INPIT