ACTIVITY INHIBITION OF RECEPTOR-TYPE TYROSINE KINASES USING RECEPTOR-TYPE TYROSINE PHOSPHATASE PTPRB

摘要

PROBLEM TO BE SOLVED: To clarify a receptor-type tyrosine kinase to become a substrate molecule of receptor-type tyrosine phosphatase Ptprb and to create new uses of Ptprb.SOLUTION: The recombinant vector for activity inhibition of a substrate selected from the group consisting of FGFR1, TYRO3, RET, EphB2, ERBB2, PDGFRa, ROS, LTK and MET comprises a promoter and a Ptprb gene operably linked to the promoter.