A RECEPTOR-TYPE TYROSINE KINASE HUMAN EPH/ELK-LIKE KINASE - HEK AND USE THEREOF

摘要

PCT No. PCT/AU92/00294 Sec. 371 Date Apr. 18, 1994 Sec. 102(e) Date Apr. 18, 1994 PCT Filed Jun. 19, 1992 PCT Pub. No. WO93/00425 PCT Pub. Date Jan. 7, 1993The present invention relates to a method of screening for ligands to a receptor-type tyrosine kinase. The receptor-type tyrosine, in its naturally occurring form, is characterized by being reactive to monoclonal antibody III.A4, having an apparent molecular weight of approximately 120-150 kD in its glycosylated form, and having the N-terminal amino acid sequence E L I P Q P.