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Substituted bisaryl and heteroaryl compounds as selective 5HT2A antagonists

机译:取代的双芳基和杂芳基化合物作为选择性5HT2A拮抗剂

摘要

The present invention relates to a series of substituted bis aryl and heteroaryl compounds of formula (I): Wherein X, Y, Z, A, B, D, Ar, R1 and R2 are as defined herein. The compounds of this invention are selective 5HT2A antagonists, and are therefore, useful in treating a variety of diseases including but not limited to a wide variety of sleep disorders as disclosed and claimed herein.
机译:本发明涉及式(I)的一系列取代的双芳基和杂芳基化合物:其中X,Y,Z,A,B,D,Ar,R 1和R 2如本文所定义。本发明的化合物是选择性的5HT2A拮抗剂,因此可用于治疗多种疾病,包括但不限于本文公开和要求保护的多种睡眠障碍。

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