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Hydrogel nanocomposite wound dressing and a method of synthesizing the same

机译:水凝胶纳米复合伤口敷料及其合成方法

摘要

The various embodiments herein provide hydrogel nanocomposite wound dressing comprising a polymeric basal matrix, a reinforcing agent, a biological sensor and an antibiotic for a slow release in a wound when applied. The polymeric basal matrix is made up of polyvinyl alcohol polymer with an amount of 1-15% by weight. The reinforcing agent comprises clay nanoparticles to inhibit a sudden drug release. The clay nanoparticles comprise montmorillonite nano particles with an amount of 0-2% by weight. The biological sensor is a peptide chain. The peptide chain is thrombin sensitive with an amount from 50 to 200 mg. The antibiotic is gentamycine with an amount of 1-3% by weight. The embodiments herein also provide a method of synthesizing the hydrogel nanocomposite wound dressing.
机译:本文的各种实施方案提供了水凝胶纳米复合伤口敷料,其包含聚合物基础基质,增强剂,生物传感器和抗生素,用于在施用时在伤口中缓慢释放。聚合物基础基质由聚乙烯醇聚合物组成,其含量为1-15%(重量)。增强剂包括粘土纳米颗粒以抑制药物的突然释放。粘土纳米颗粒包含0-2重量%的蒙脱土纳米颗粒。生物传感器是一条肽链。肽链对凝血酶敏感,用量为50至200 mg。抗生素是庆大霉素,含量为1-3%(重量)。本文的实施方案还提供了合成水凝胶纳米复合伤口敷料的方法。

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