首页>
外国专利>
Tracers for monitoring the activity of sodium/glucose cotransporters in health and disease
Tracers for monitoring the activity of sodium/glucose cotransporters in health and disease
展开▼
机译:示踪剂,用于监测钠/葡萄糖共转运蛋白在健康和疾病中的活性
展开▼
页面导航
摘要
著录项
相似文献
摘要
Radiolabeled tracers for sodium/glucose cotransporters (SGLTs), their synthesis, and their use are provided. The tracers are methyl or ethyl pyranosides having an equatorial hydroxyl group at carbon-2 and a C 1 preferred conformation, radiolabeled with 18F, 123I, or 124I, or free hexoses radiolabeled with 18F, 123I, or 124. Also provided are in vivo and in vitro techniques for using these and other tracers as analytical and diagnostic tools to study glucose transport, in health and disease, and to evaluate therapeutic interventions.
展开▼