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process for the production of optically pure (-) - (s) - 6.4 - dihydroksyflawanonu

机译:光学纯(-)-(s)-6.4的制备方法-dihydroksyflawanonu

摘要

process for the production of optically pure (-) - (s) - 6.4 - dihydroksyflawanonu, model 2, is that the prepared medium introduces strain aspergillus niger mb and at the time of the final phase of logarithmic growth, the fungus, the following 6 - butyryloksyflawanon in quantities of 10 mg per 100 ml of the medium.the transformation process is water culture microbial strain in continuous wstrzu0105saniu, as a result, with the participation of the enzyme system strain, followed by hydrolysis, binding estrowego in item 6, followed by hydroxylation in position 4 'substrate 6 - butyryloksyflawa nonu.the resulting product is extracted with an organic solvent niemieszaju0105cym with water and purifies chromatograficznie.
机译:光学纯的(-)-(s)-6.4-dihydroksyflawanonu(模型2)的制备方法是,制备的培养基引入了黑曲霉菌株mb,在对数生长期的最后阶段,真菌,以下6种-每100毫升培养基中10毫克丁酰基黄酮。转化过程是连续wstrz u10105saniu中的水培养微生物菌株,其结果是酶体系菌株参与,随后水解,结合了estrowego中的第6项,然后在4'位底物6-butyryloksyflawa nonu上进行羟基化。所得产物用有机溶剂niemieszaj u105cym用水萃取并纯化色谱层析。

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