the optically pure (-) - (s) - 6.4 - dihydroksyflawanon and way to produce optically pure (-) - (s) - 6.4 - dihydroksyflawanonu

摘要

the subject invention is optically pure (-) - (s) - 6.4 - dihydroksyflawanon, model 2 and the way of its manufacture.way is characterized by the fact that the prepared medium introduces strain aspergillus niger mb and at the time of the final phase of logarithmic growth, the fungus, the following 6 - acetoksyflawanon in quantities of 10 mg per 100 ml of the medium, whereby the transition process mikrobiologiczn hey is water culture strain in continuous wstrzu0105saniu, resulted inwith the involvement of the enzyme system strain, followed by hydrolysis, binding estrowego in item 6, followed by hydroxylation in position 4 '- acetoksyflawanonu substrate 6. the resulting product is extracted with an organic solvent niemieszaju0105cym with water and purifies chromatograficznie.