the optically pure (+) - (r) - 6.4 - dihydroksyflawanon and way to produce optically pure (+) - (r) - 6.4 - dihydroksyflawanonu

摘要

the subject invention is optically pure (+) - (r) - 6.4 - dihydroksyflawanon, model 2 and process for the production of optically pure (+) - (r) - 6.4 - dihydroksyflawanonu, model 2, characterised by the fact that the prepared medium introduces strain aspergillus niger mb and at the time osiu0105gni the final phase of logarithmic growth participate by fungus.the following 6 - metoksyflawanon in quantities of 10 mg per 100 ml of the medium, and microbial transformation process is water culture strain in continuous wstrzu0105saniu, as a result, with the participation of the enzyme system strain, followed by demethylation in position 6, and then hydroks ylacja in position 4 'substrate 6 - methoxy - flawanonu.the resulting product is extracted with an organic solvent niemieszaju0105cym with water and purifies chromatograficznie.