AUTOMATED ANALYSIS OF MULTIPLEXED PROBE-TARGET INTERACTION PATTERNS: PATTERN MATCHING AND ALLELE IDENTIFICATION

摘要

Methods and algorithms for automated allele assignments are providedwithin an integrated software environment. These methods and algorithmsoffer a multiplicity of functionalities including: data management; systemconfiguration including user authorization, training set analysis and probemasking; pattern analysis including string matching and probe flipping; andinteractive redaction of data. The methods and algorithms further includemethods of setting thresholds, refining thresholds, and probe masking ofsignals produced by probes which do not contribute significantly todiscriminating among alleles.