PHARMACEUTICAL COMPOSITION HAVING SYNERGISTIC ACTION OF DIRECT CATALASE INHIBITORS AND MODULATORS OF NO METABOLISM OR OF EXTRACELLULAR SUPEROXIDE ANION PRODUCTION WHICH LEAD TO CATALASE DESTRUCTION

摘要

The present patent application relates to a pharmaceutical composition, characterized in that it comprises at least one active ingredient which can bring about a singlet oxygen-independent direct catalase inactivation, and in that the composition further comprises at least one active ingredient which leads to inactivation of catalase as a result of modulation of the nitrogen oxide or superoxide anion metabolism of the cells and subsequent singlet oxygen formation.