首页> 外国专利> Pharmaceutical Composition Having Synergistic Action Of Direct Catalase Inhibitors And Modulators Of NO Metabolism Or Of Extracellular Superoxide Anion Production Which Lead To Catalase Destruction

Pharmaceutical Composition Having Synergistic Action Of Direct Catalase Inhibitors And Modulators Of NO Metabolism Or Of Extracellular Superoxide Anion Production Which Lead To Catalase Destruction

机译:具有直接过氧化氢酶抑制剂和NO代谢调节剂的协同作用或导致过氧化氢酶破坏的细胞外超氧阴离子产生调节剂的药物组合物

摘要

The present patent application relates to a pharmaceutical composition, characterized in that it comprises at least one active ingredient which can bring about a singlet oxygen-independent direct catalase inactivation and that the composition further comprises at least one active ingredient that leads to inactivation of catalase as a result of modulation of the nitrogen oxide or superoxide anion metabolism of the cells and subsequent singlet oxygen formation.
机译:本专利申请涉及一种药物组合物,其特征在于它包含至少一种可引起单重态氧非依赖性直接过氧化氢酶失活的活性成分,并且该组合物还包含至少一种导致过氧化氢酶失活的活性成分。调节细胞中氮氧化物或超氧阴离子代谢以及随后形成单线态氧的结果。

著录项

  • 公开/公告号US2015335663A1

    专利类型

  • 公开/公告日2015-11-26

    原文格式PDF

  • 申请/专利权人 UNIVERSITAETSKLINIKUM FREIBURG;

    申请/专利号US201314410221

  • 发明设计人 GEORG BAUER;

    申请日2013-06-20

  • 分类号A61K31/60;C07K16/40;A61K31/337;A61K31/26;A61K31/05;A61K31/496;A61K31/4164;A61K31/352;A61K31/105;

  • 国家 US

  • 入库时间 2022-08-21 14:36:01

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