PHARMACEUTICAL COMPOSITION COMPRISING ACECAINIDE OR DERIVATIVE THEREOF FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH MUSCULAR WEAKNESS

摘要

The present invention relates to a composition for promoting differentiation of myoblast, comprising Acecainide or Procainamide which is a derivative of Acecainide, or pharmaceutically acceptable salts of Acecainide, to a method for promoting differentiation of myoblast, comprising a step of treating in vitro myoblast with Acecainide or Procainamide which is a derivative of Acecainide, or pharmaceutically acceptable salts of Acecainide, to a method for preparing differentiated myoblast, comprising a step of differentiating myoblast by treating in vitro myoblast with Acecainide or Procainamide which is a derivative of Acecainide, or pharmaceutically acceptable salts of Acecainide, to a pharmaceutical composition for preventing or treating diseases associated with muscular weakness and to a food composition for preventing or treating diseases associated with muscular weakness, comprising Acecainide or Procainamide which is a derivative of Acecainide, or pharmaceutically acceptable salts of Acecainide. The invention further relates to a method for treating diseases associated with muscular weakness, comprising a step of administering Acecainide or Procainamide which is a derivative of Acecainide, or pharmaceutically acceptable salts of Acecainide to an individual who needs same. The Acecainide or Procainamide which is a derivative of Acecainide according to the present invention may promote differentiation of myoblast to form muscle canal, and therefore said composition may prevent muscular weakness and improve muscular function in an effective manner. Thus, the pharmaceutical composition comprising the Acecainide or Procainamide which is a derivative of Acecainide can be effectively used in preventing or treating diseases associated with muscular weakness.