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NANOLIPOSOME USING ESTERIFIED LECITHIN AND METHOD FOR PREPARING THE SAME, AND COMPOSITION FOR PREVENTING OR TREATING SKIN DISEASES COMPRISING THE SAME

机译:使用酯化卵磷脂的纳米脂质体及其制备方法,以及用于预防或治疗包含该脂质体的皮肤疾病的组合物

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The patent describes a delivery system comprising a liposome membrane containing esterified lecithin and one or more physiologically active ingredients. The esterified lecithin is a reaction product of hydrogenated lecithin and an organic acid, preferably anhydrous malic acid or anhydrous acetic acid. If anhydrous acetic-acid is used, the esterified lecithin shows greater hydrophilicity than with anhydrous malic acid. Thus, the organic acid can be selected appropriately, depending on the relative amounts of hydrophilic or hydrophobic functional material to be added and its degree of polarity. The organic acids are also keratolytic and skin softening.
机译:该专利描述了包括脂质体膜的递送系统,该脂质体膜包含酯化的卵磷脂和一种或多种生理活性成分。酯化的卵磷脂是氢化卵磷脂与有机酸,优选无水苹果酸或无水乙酸的反应产物。如果使用无水乙酸,则酯化的卵磷脂显示出比无水苹果酸更大的亲水性。因此,可以根据要添加的亲水性或疏水性功能材料的相对量及其极性来适当地选择有机酸。有机酸还具有角质分解作用和皮肤柔软作用。

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