ANDROGRAPHIS PANICULATA EXTRACT AND PHARMACEUTICAL COMPOSITION COMPRISING THE EXTRACT AND USE IN THE MANUFACTURE OF PHARMACEUTICAL COMPOSITION OF THE EXTRACT

摘要

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for effectively treating inflammatory bowel disease or ulcerative colitis.SOLUTION: The pharmaceutical composition for treating inflammatory bowel disease or ulcerative colitis comprises an andrographis paniculata extract. The extract comprises andrographolide lactones comprising andrographolide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, and neoandrographolide, in amounts ranging from 2% to 20%, 0.01% to 2%, 1% to 6%, and 1% to 5% of the dry weight of the extract, respectively, and further comprises dextrin and at least one pharmaceutically acceptable carrier. In a human clinical trial, the pharmaceutical composition has been shown to be effective for treating inflammatory bowel disease or ulcerative colitis in a human.