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AGENT, PHARMACEUTICAL COMPOSITION, AND METHOD FOR TREATING THE ETHYL ALCOHOL AND/OR NARCOTIC DEPENDENCE

机译:药剂,药物组合物和用于治疗乙基醇和/或麻醉依赖性的方法

摘要

The invention relates to the area of the chemical-pharmaceutical industry and medicine, in particular, to an agent for treatment of dependence on ethyl alcohol and/or drugs, treatment of psychosomatic and neurological complications in such patients; to pharmaceutical compositions containing this agent; and to treatment methods for psychosomatic and neurological complications with this agent.;The aim of the invention is to develop a new pharmaceutical agent with minimal side effects.;The proposed therapeutic substance, for treatment of addiction to ethanol and/or drugs, for treatment of psychosomatic and neurological complications in such patients, which is presented by polyprenols of formula (1); embedded image ;where n=8-20.;Therapeutic composition for treatment of addiction to ethanol and/or drugs, for treatment of psychosomatic and neurological complications in patients is suggested, which includes an effective amount of polyprenols of formula (1); embedded image ;where n=8-20.and pharmaceutically acceptable excipients, including carriers, and/or solvents. Pharmaceutical composition may be executed in the form of a solution, suspension, capsule, tablet, liposome form.Attached is the use of polyprenols of formula (1); embedded image ;where n=8-20as an active ingredient of the pharmaceutical composition for treatment of addiction to ethanol and/or drugs, for treatment of psychosomatic and neurological complications in such patients.;Attached is the method of treatment of addiction to ethanol and/or drugs, for treatment of psychosomatic and neurological complications in such patients, which differs in that it includes administration of polyprenols of formula (1).;From the above-mentioned results of the study of the therapeutic substance based on compound of formula (1) conducted in the clinic, one is able to conclude the efficacy of the treatment for addiction to ethyl alcohol and/or drugs, on recovering of abstinence syndrome, and on the improvement of psychosomatic state in patients, as well as on significant improvement of neurological disorders and/or complete regression of polyneuropathy.;It is important to note, that Ropren is well tolerated by patients and side effects, allergic reactions and impairments were not found in any patient in the experimental group for the whole period of treatment.
机译:本发明涉及化学制药工业和医学领域,尤其涉及一种用于治疗依赖于乙醇和/或药物,治疗这类患者的心身和神经并发症的药剂。含有该试剂的药物组合物;本发明的目的是开发一种副作用最小的新药物。所提出的治疗物质,用于治疗乙醇和/或药物成瘾,用于治疗式(1)的聚戊二烯醇对这类患者的心身和神经系统并发症的影响; “嵌入式图像” ;其中n = 8-20 。;提出了用于治疗乙醇和/或药物成瘾,用于治疗患者的心身和神经系统并发症的治疗组合物,其包括有效量的式(1)的聚戊烯醇; “嵌入式图像” ;其中n = 8-20。和药学上可接受的赋形剂,包括载体和/或溶剂。药物组合物可以以溶液,悬浮液,胶囊,片剂,脂质体形式的形式执行。附带的是式(1)的聚戊烯醇的使用; “嵌入式图像” ;其中n = 8-20作为用于治疗乙醇和/或药物成瘾,用于治疗此类患者的心身和神经系统并发症的药物组合物的活性成分,其是有效的。;附有治疗乙醇和/或药物成瘾的方法,用于治疗这类患者的心身和神经系统并发症,其不同之处在于,它包括施用式(1)的聚戊烯醇。在临床上对基于式(1)的化合物的治疗物质进行的研究,能够得出结论:治疗酒精和/或药物成瘾,戒断综合症的恢复以及对戒毒的改善的疗效。患者的心身状态,以及神经系统疾病的显着改善和/或多发性神经病的完全消退。;重要的是要注意,患者对Ropren的耐受性良好,并且在任何患者中均未发现副作用,变态反应和功能障碍在整个治疗期间的实验组中。

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