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Process for preparing carboxylic acid amides useful in the treatment of muscular disorders
Process for preparing carboxylic acid amides useful in the treatment of muscular disorders
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机译:制备可用于治疗肌肉疾病的羧酸酰胺的方法
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摘要
The present invention relates to a process for preparing a compound of formula wherein: R2 is cycloalkyl or alkyl, each of which may be optionally substituted; Y is —CONR3R4, —CN or CO2R5; R3, R4 and R5 are each independently H or alkyl; n is 1 to 6; wherein said process comprising the steps of: (i) treating a compound of formula (IV), where R1 is alkyl, with a compound of formula (V) and forming a compound of formula (IIIb); (ii) treating said compound of formula (IIIb) with a compound of formula (I1) to form a compound of formula (I).; 展开▼
机译:本发明涉及一种制备下式化合物的方法,其中:R Sup 2是环烷基或烷基,它们各自可以被任选取代。 Y是-CONR 3 Sup> R 4 Sup>,-CN或CO 2 Sub> R 5 Sup>; R 3 Sup>,R 4 Sup>和R 5 Sup>分别独立地为H或烷基; n为1至6;其中所述方法包括以下步骤:(i)用式(V)化合物处理式(IV)的化合物,其中R Sup 1是烷基,并形成式(IIIb)的化合物; (ii)用式(I1)化合物处理所述式(IIIb)化合物以形成式(I)化合物。 化学>
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