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Compounds, pharmaceutical composition, pharmacological agent efficacy enhancing methods and compound screening for use as mrp inhibitors and their uses
Compounds, pharmaceutical composition, pharmacological agent efficacy enhancing methods and compound screening for use as mrp inhibitors and their uses
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机译:用作mrp抑制剂的化合物,药物组合物,药理药功效增强方法和化合物筛选及其用途
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摘要
5-Quinolinone and Imidazopyrimidine compounds are provided that are useful for inhibiting the efflux of any therapeutic agent that is a MRP1 substrate. Also provided is a method for screening to identify additional MRP1 inhibitors.
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